Lionel Messi will miss Paris Saint-Germain's Champions League match against Benfica on Tuesday because of a minor leg injury, the French club has said.
Argentina forward sat out PSG's goalless draw at Reims in the French league over the weekend because of the pain in one of his calves.
He had first felt the discomfort in his leg toward the end of the 1-1 draw at Benfica last week when the teams first met in Group H.
PSG said in a statement that Messi is not yet ready to play.
It read: 'Nursing a calf niggle, Lionel Messi will not make the game against Benfica.'
Presnel Kimpembe, Nuno Mendes, and Renato Sanches will also miss the game with longer-term issues.
Messi opened the scoring in PSG's 2-1 win over Nice at the start of the month and scored a screamer in last week's 1-1 draw in the reverse fixture but missed the draw with Reims, which saw Sergio Ramos sent off.
PSG and Benfica are both unbeaten in three matches and even on points at the top of the group, which also includes Juventus and Maccabi Haifa.
Roger Schmidt's side, who are top of the Portuguese Primeira Liga with eight wins from nine games, beat Juve 2-1 in the second round of matches after defeating Maccabi Haifa 2-0.
The match in Paris could go a long way to determining who qualifies for the knockout stages as group winners.
PSG FULL PLAYER LIST
| Full Player List |
|---|
| 1. Keylor Navas |
| 2. Achraf Hakimi |
| 4. Sergio Ramos |
| 5. Marquinhos |
| 6. Marco Verratti |
| 7. Kylian Mbappé |
| 8. Fabian Ruiz |
| 10. Neymar Jr |
| 14. Juan Bernat |
| 15. Danilo Pereira |
| 16. Sergio Rico |
| 17. Vitinha |
| 19. Pablo Sarabia |
| 26. Nordi Mukiele |
| 28. Carlos Soler |
| 31. El Chadaille Bitshiabu |
| 33. Warren Zaïre-Emery |
| 35. Ismaël Gharbi |
| 44. Hugo Ekitike |
| 99. Gianluigi Donnarumma Source |